초록 |
Polyurethane (PU) nanofibers were prepared by using electrospinning. The as-spun PU nanofibers were dip-coated with rosin, cactus, silver and Scutellariae Radix to obtain composite nanofibers. The morphology, structure and thermal characteristics of resultant PU composite nanofibers were analyzed by SEM, XRD, FT-IR, TGA, and Raman spectroscopy. The antimicrobial activity of the pristine and PU nanofibers containing composite materials were tested against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) by minimum inhibitory concentration (MIC) method. From the disc diffusion test, the antimicrobial efficacy of the PU composite nanofibers was greater than that of pristine PU nanofibers. The PU composite nanofibers exhibited excellent antimicrobial property towards S. aureus and E. coli bacterial strains. This study encourages the application of the electrospun rosin based fibers for biomedical applications such as prolonged wound dressing materials. |