화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 봄 (04/09 ~ 04/10, 대전컨벤션센터)
권호 34권 1호
발표분야 기능성 고분자
제목 Preparation of Carboxymethyl Chitosan using Low Molecular Weight Water Soluble Chistsan as an ion-complex delivery
초록 Carboxymethyl chitosan(CMCh) was prepared by chemical reaction of mono-chloroacetic acid and glyoxylic acid with low molecular weight water soluble chitosan(LMWSC). By chage of the reaction protocol, O-Carboxymethyl chitosan(C6-OH), N-Carboxymethylc chitosan (C2-NH2), and N,O-Carboxymethyl chitosan (C6-OH and C2-NH2) were synthesized to apply as an ionic-drug carrier. The structure were characterized by Fourier transform infrared (FT-IR), 1H-NMR, 13C-NMR, DEPT and HMQC (Heteronuclear Multiple Quantum Correlation). Degree of substitution (DS) and degree of deacetylation(DDA) of CMCh was determined by 1H-NMR.
저자 남정표, 허선행, 정현, 정영일, 김동곤, 장미경, 나재운
소속 순천대
키워드 carboxymethyl chitosan; LMWSC; ion-complex; DEPT; HMQC.;
E-Mail