| 초록 |
Self-assembly, a process in which small building blocks spontaneously form fine structures, is centrally important in life and has a great potential for fabricating novel materials as well. The self-assembly of peptides into amyloid aggregates is a pathological hallmark of many neurodegenerative diseases such as Alzheimer’s, Parkinson’s, mad cow, and other life-threatening diseases. I will present our results about template-directed formation of amyloid aggregates and amyloid lawn system for high-throughput analysis of amyloid toxicity/drug screening. Also, our recent development of a novel process for solid-phase growth of vertically well-aligned peptide nanowires will be introduced with its applications. |
