화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2005년 봄 (04/22 ~ 04/23, 여수대학교)
권호 11권 1호, p.677
발표분야 열역학
제목 Synthesis and antimicrobial properties of ionic liquids
초록 For the purpose of developing new disinfectants and antiseptics, we searched for compounds having high bactericidal activity against gram-positive bacteria, gram-negative bacteria, and fungi. Three different series of quaternary imidazolium and pyrrolidinonium salts were synthesized.
These three series were tested to evaluate their antibacterial and antifungal properties for the first time. Seven microbial strains were used in the study.
The antimicrobial efficiency was measured by bacterial and fungal growth inhibition expressed as minimal inhibitory concentration (MIC) values.
Among the synthesized quaternary imidazolium and pyrrolidinonium salts, the imidazolium salts containing a long alkyl chain and the introduction of a hydroxyethyl chain and methyl group into the imidazolium ring structure leads to broad spectrum active antimicrobial agents which not only have bacteriostatic properties but could be powerful bactericides.
저자 최숙정, 김기섭, 연순화, 차종호, 이 흔
소속 한국과학기술원
키워드 imidazolium salt; morpholinium salt
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