| 초록 |
The poly(methyl methacrylate) (PMMA), mainstream substance used for commercial acrylic bone cement (ABC), have intrinsic characteristics such as biocompatibility, easy processability, and high mechanical strength. In this study, we substituted pristine PMMA powder with hypo-crystallized-PMMA(hc-PMMA) powder and bioactive glass 45S5. The unique nanostructure and high modulus of the hc-PMMA itself have enhanced the compressional strength of resulting bone cement. Due to the high surface area and internal strain formed by the crystallization process, the addition of hc-PMMA dramatically decreased the polymerization time without any additional catalyst. Finally, the resulting bone cement showed high osteoconductivity than the pristine ABC composite, confirmed by the simulated body fluid (SBF) test. Based on the results, hc-PMMA and bioactive glass 45S5 incorporated bone cement can be an optimal candidate for the long-term fixation of the load-bearing implants. |
