| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 봄 (04/10 ~ 04/12, 부산컨벤션센터(BEXCO)) |
| 권호 |
44권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Nitrogen Containing PAG Photochemically Induced Singlet Oxygen via New Mechanistic Pathway |
| 초록 |
Singlet oxygen generators containing conjugated aromatic groups or heavy metal atom have shown good efficacy in photodynamic therapy, however, most of them displayed limitations as therapeutic agents due to poor biocompatibility. Herein, we introduce a new type of singlet oxygen generator based on aliphatic polyaminoglycerols (PAG) with superior biocompatibility. It was confirmed that nitrogen atom on the backbone of PAG was responsible for the electron transfer owing to its paramagnetic properties that generates radical oxygen species, and subsequently converted to singlet oxygen. |
| 저자 |
홍영주1, 김병수1, 권태혁2, 남정승2, 이채규2, 이채헌2
|
| 소속 |
1연세대, 2울산과학기술원 |
| 키워드 |
PAG; Singlet Oxygen; Biocompatibility
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| E-Mail |
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