| 학회 | 한국화학공학회 |
| 학술대회 | 2009년 가을 (10/22 ~ 10/23, 일산 KINTEX) |
| 권호 | 15권 2호, p.1601 |
| 발표분야 | 생물화공 |
| 제목 | Fabrication of ITO electrode for cell chip to detect the effects of environmental toxicants on PC12 cells |
| 초록 | Indium Tin Oxide (ITO) substrates are highly desirable at the development of cell-based chip.In this study, PC12 cells were immobilized on an oligopeptide modified ITO surface for improving the cell attachment.Cells were further treated with the nerve growth factor to induce neurite outgrowth and then,effects of environmental toxicity were examined by cyclic voltammetry.The cyclic voltammetry study determined the inverse linear relationship between the concentrations of environmental toxins and current peak at specific potential.This research has a number of potential applications to cell based electrical biosensors and neuronal prosthetic devices. Acknowledgments: This research was supported by the Korea science and Engineering foundation (KOSEF) grant funded by the Korea government (MEST) (2009-0088060) and by the Nano/Bio science & Technology Program (M10536090001-05N3609-00110) of the Ministry of Education, Science and Technology (MEST) and by Ministry of Environment of the Republic of Korea as "The Eco-technopia 21 project" |
| 저자 | Rama Bhusal, 김태형, 김현철, 최정우 |
| 소속 | 서강대 |
| 키워드 | ITO electrode; Cyclic voltammetry; PC12 Cells; Neurite growth; Environmental toxin |
| 원문파일 | 초록 보기 |
