| 학회 | 한국고분자학회 |
| 학술대회 | 2005년 가을 (10/13 ~ 10/14, 제주 ICC) |
| 권호 | 30권 2호 |
| 발표분야 | 기능성 고분자 |
| 제목 | Synthesis and Characterization of Polyurethane Nanocapsules by Interfacial Polycondensation |
| 초록 | Polyurethane nanocapsules were synthesized and were chosen as drug carriers for trans-retinol. This active ingredient is widely used as an anti-wrinkle agent in the cosmetic application. But it could be rapidly degraded in the atmosphere, because of its poor light, heat and oxygen sensitivity. Thus polyurethane nanocapsules were synthesized by interfacial reaction between two monomers. Interfacial polycondensation combined with spontaneous emulsification is a new technique for nanocapsule formation. Nanocapsules were characterized by measuring the particle size (300~500nm), pH, yield of encapsulation and morphologies. Polyurethanes (PUR) were obtained from the condensation of diisocyanate (4,4-Diphenylmethane diisocyanate : MDI ) with several polyols. Molecular weights of polyols had a considerable influence on nanoparticles characteristics cited above. The increase of molecular weight of polyols tended to increase the mean size of nanocapsules. The results showed that the yield of encapsulation was increased with the increase of molecular weight of polyols. Reference 1. S. Kwon. Langmuir, 19, 10188 (2003) 2. R. Maruca and B. T. Suder, J. Appl. Polym. Sci., 27, 4827 (1992) 3. K. Y. Lee, Langmuir, 14, 2329 (1998) 4. K. Y. Lee, Macromolecules, 31, 378 (1998) 5. M. Schmitt and M. Kietzmann, J. Cosmet. Sci., 50, 147 (1997). |
| 저자 | 이천일1, 신재섭2 |
| 소속 | 1한불화장품 (연), 2충북대 |
| 키워드 | polyurethane; nonoparticle; interfacial polycondensation |
