| 학회 |
한국화학공학회 |
| 학술대회 |
2012년 가을 (10/24 ~ 10/26, 부산 BEXCO) |
| 권호 |
18권 2호, p.1838 |
| 발표분야 |
생물화공 |
| 제목 |
Synthesis of protein nanowire for using three-dimensional bioassy |
| 초록 |
In order to construct highly efficient diagnostic system, we designed bifunctional protein nanowire. S protein nanowires were genetically engineered and used as diagnostic probes for the antibody detection. Biotin binding peptide (BBP) and antigenic epitope of auto immune disease antigen (IDA) were fusion expressed with S protein, and were formed bifunctional protein nanowire through spontaneous assembly. And we construct 3-dimensional diagnostic system to detect auto IDA. The results showed that the signal intensities and sensitivities of 3-dimenstional diagnostic system increased much higher than those of 2-dimensional flat surface.
|
| 저자 |
김현진, 박동현, 이은아, 이지원
|
| 소속 |
고려대 |
| 키워드 |
bioassy; protein nanowire
|
| E-Mail |
|
| 원문파일 |
초록 보기 |
