화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2013년 가을 (10/23 ~ 10/25, 대구 EXCO)
권호 19권 2호, p.1501
발표분야 생물화공
제목 CoryneBrick: Synthetic Biology platform for the optimal expression of the target gene in Corynebacterium glutamicum 
초록 Recent development of synthetic platforms for the production of industrial interests have been developed and implemented to microbial cells. However, most synthetic tools have been targeted well known bacteria such as Escherichia coli and Saccharomyces cerevisiae. Here we expanded a synthetic biology platform of gene expression vectors applicable in Corynebacterium glutamicum, known industrial amino acid producers. We developed the CoryneBrick vectors featuring E.coli-C. glutamicum shuttle vectors with different origins of replication and controllable promoters. CoryneBrick were applied to the biofuel production system in C. glutamicum, which could be another example of industrial Corynebacteria. This work was supported by the National Research Foundation of Korea Grant funded by the Korean Government (MEST) (2013, University-Institute cooperation program) and ‘Creative Allied Program (CAP)’ through the Korea Research Council of Fundamental Science and Technology (KRCF) and Korea Institute of Science and Technology (KIST).
저자 우한민, 강민경, 이정석, 엄영순
소속 한국과학기술(연)
키워드 합성생물학; 코리네박테리움
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