| 학회 | 한국고분자학회 |
| 학술대회 | 2003년 봄 (04/11 ~ 04/12, 연세대학교) |
| 권호 | 28권 1호, p.329 |
| 발표분야 | 기능성 고분자 |
| 제목 | Variation in Volume Transition Temperature and Swelling Behavior of Temperature-Responsive Hydrogels by Copolymerization |
| 초록 | Temperature-responsive hydrogels were prepared with the combination of various hydrophilic and hydrophobic monomers. N-isopropylacrylamide (NIPAAm) and acrylamide (AAm) were chosen as the hydrophilic monomer and n-butoxymethylacrylamide (nBMA) was chosen as the hydrophobic monomer. Poly(ethylene glycol) methyl ether methacrylate (PEG) was chosen as the macromonomer for the hydrophilic graft. Both slab gel and microgel were prepared by photopolymerization. Both volume transition and swelling behavior were studied for the hydrogels prepared with these monomers. Volume transition and swelling behaviors were fast and thermally reversible. g-Aminobutyric acid(GABA)-releasing behavior was studied for these PEG-grafted hydrogels. Poly(NIPAAm) hydrogel showed the sensitivity to the thermal stimuli at around 30°C with a large volume change. The transition temperature was controlled by incorporating other monomers. nBMA was incorporated in a proper composition for the preparation of thermal stimuli-sensitive hydrogels which had a sharp volume transition temperature around 15°C. Volume transition temperature and degree of swelling were varied significantly depending on the content of comonomer, graft, and crosslinker. |
| 저자 | 이제용;김형일 |
| 소속 | 충남대 |
| 키워드 | Temperature sensitive Hydrogel; Volume transition; Swelling behavior; |
