화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2014년 가을 (11/12 ~ 11/14, 엑스코(대구))
권호 18권 2호
발표분야 나노-포스터
제목 Folic acid with Pyrenemethylamine Amidaion after Chemically Reduced Graphene Oxide through π-π Interaction for Cancer Targeting Sensor
초록  Single-sheet graphene given the excellent in-plane mechanical, structural, thermal, and electrical properties. Thus, a large amount of material can be attached to graphene due to a large surface area of graphene via π-π interaction. Folic acid (FA) can target cancer via folic acid receptors, Pyrenemethylamine (PMA) can luminescence because of pyrene group have a structure of four fused benzene rings. Advantage of using, we synthesized that Folic acid-Pyrenemethylamine (FA-PMA) was formed by condensation of the carboxyl group of FA with the amine group of PMA through amide formation. Before, Folic acid-Pyrenemethyl-amine (FA-PMA) attached on chemically reduced graphene oxide (RGO) through π-π interaction. In this study, we expected that RGO/Folic acid-Pyrenemethylamine can be used not only luminescence sensor but also drug delivery for targeting cancer.
저자 류형선, 박영호, 김석준, 조성호, 손영지, 유종영, 인인식
소속 한국교통대
키워드 Folic acid; Pyrenemethylamine; RGO
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