| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Tethered Lipid Bilayer on Titanium Surfaces for Controlled Release of Nitric Oxide |
| 초록 |
The aim of this study is to investigate the feasibility and potential use of tethered supported lipid bilayer (TLB) coating on stent with a lipophilic NO donor incorporated within the phospholipid bilayer, to achieve a NO controlled and sustained release rate. Surface characterizations including confocal microscopy and atomic force microscopy (AFM) showed successful bilayer formation on the surface of titanium. NO release profiles were sustained up to 24 hrs. In vitro cell study demonstrated that NO release enhanced endothelial cell proliferation. Finally, these results open a door for the potential use of TLB coating that utilizes therapeutic agents in biomedical devices. |
| 저자 |
Mahmoud amr Elnaggar, 김가을, 정윤기
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| 소속 |
한국과학기술(연) |
| 키워드 |
tethered lipid bilayer; nitric oxide; nitrated lipids.
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| E-Mail |
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