| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
20권 2호 |
| 발표분야 |
나노_포스터 |
| 제목 |
Carbon Nanotube Hybrids for Optical Detection of proPSAs |
| 초록 |
Multiplex detection and discrimination of prostate-specific antigen (PSA) and proPSA including [-2]proPSA, [-5]proPSA and [-7]proPSA in blood are considered to be a promising way to improve the accuracy of prostate cancer detection. We developed the nanoprobes producing strong resonance Raman scattering signals by controlling the orientation and density of tandem antibodies specific for proPSAs on single-walled carbon nanotubes (SWNTs), denoted pSNA, for multiplex detection of PSA derivatives. The pSNAs showed an enhanced binding affinity to the target molecules, and they were able to selectively detect [-2]proPSA, [-5]proPSA, and [-7]proPSA captured on the magnetic beads. |
| 저자 |
김혜인, 전수지, 임다빈, 강태욱, 김만진, 김종호
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| 소속 |
한양대 |
| 키워드 |
Carbon nanotube; Tandem antibody; Nanohybrid; PSA; proPSA; Multiplex detection
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| E-Mail |
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