| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 가을 (10/10 ~ 10/12, 경주컨벤션센터) |
| 권호 |
43권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 I(영어발표) |
| 제목 |
Combination of Image-guided Intervention and Functional Polymeric Microspheres for Effective Hepatocellular Carcinoma (HCC) Treatment |
| 초록 |
Hepatocellular carcinoma (HCC) is a fatal disease with high mortality worldwide. In particular, treatment options are more limited in inoperable HCC. Image-guided intervention has been considered as a useful targeted delivery technique for the inoperable liver tumors. In this study, a novel HCC treatment technique using a combination of image-guided intervention and functional polymeric microspheres was demonstrated. The functional polymeric microspheres containing drugs and iron oxide nanoparticles for magnetic resonance (MR) imaging were successfully prepared. The microspheres injected locally through the hepatic artery effectively delivered the drugs to the tumor site, inhibiting angiogenesis in the tumor microenvironment (TME) or enhancing the infiltration of immune cells. We believe that the combination of image-guided intervention with functional polymeric microspheres will have great potential for inoperable liver tumors. |
| 저자 |
박우람 |
| 소속 |
차의과학대 |
| 키워드 |
Hepatocellular carcinoma (HCC); Image-guided intervention; Polymeric Microspheres; Magnetic Resonance (MR) Imaging
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| E-Mail |
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