| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Gold Nanorods-Containing Microparticles for Phototermal Therapy |
| 초록 |
Gold nanorods (GNRs) recently have been known as an effective photothermal therapeutics utilizing enhanced NIR absorbance with adjustable optical properties and larger cross sections by controlling aspect ratios. However, there exist intrinsic problems of nanoparticles, the nanotoxicity caused by accumulation out of target, pose a question of photothermal therapy using nano-sized agents. Herein, we present a method encapsulating GNRs into PEG based radical polymer networks via stop flow lithography, which enables anisotropic, multifunctional and uniform microparticles. These microparticles have two notable properties: (1) They can be implanted into a specific site with relatively large size maintaining similar optical properties and photothermal effects compared to bare GNRs. (2) GNRs can be immobilized in microparticles, preventing the toxicity. Overall, in vivo experimental results support these properties of GNRs. |
| 저자 |
문현준1, 구민희2, 노윤호1, 윤나라2, 이준호1, 양재문2, 봉기완1
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| 소속 |
1고려대, 2연세대 |
| 키워드 |
Microparticles; Gold Nanorods; Photothermal Therapy
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| E-Mail |
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