화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2010년 봄 (04/22 ~ 04/23, 대구 EXCO)
권호 16권 1호, p.374
발표분야 생물화공
제목 Biosynthesis of gamma aminobutyric acid (GABA) from L-glutamate (MSG) by Lactobacillus strains
초록 Gamma aminobutyric acid (GABA) is the non-essential amino acid not found in natural proteins and is found in the human brain and eyes. It serves as a major inhibitory neurotransmitter with hypertensive and diuretic effects in animals. GABA has been applied in health functional foods, which may promote relaxation and relieve nervous tension.
Recently, bio-based fuels and polymers have become important due to the increase of oil price and concerns about environmental pollution. Because GABA is the possible monomer for nylon 4, which is the biodegradable heat-resistant polymer, production of GABA from cheap carbon source such as L-glutamate (MSG) become important in an industrial point of view.In this work, we have carried out whole cell reaction for the production of GABA from L-glutamate using various Lactobacillus strains. Reaction conditions affecting GABA production including temperature, pH, and initial L-glutamate concentration were examined.
저자 박시재1, 이승환1, 김민정1, 김은영1, 최민정1, 엄경태1, 송봉근1, 이은교2
소속 1한국화학(연), 2한국생명공학(연)
키워드 GABA; MSG; Lactobacillus; GAD
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