초록 |
Using a simple fluidic device fabricated with a PVC tube, a syringe needle, and a glass capillary tube, we produced uniform microspheres from natural and synthetic polymers. We prepared uniform, porous PLGA beads with controllable pore sizes by employing unstable water-in-oil emulsion as the discontinuous phase, which can be useful for therapeutic cell delivery and tissue engineering. In addition, uniform PLGA microbeads with a hollow interior and porous wall were prepared using a fluidic device with three-way channels. We developed inverse opal scaffolds from chitosan and poly(D,L-lactide-co-glyclide) (PLGA) by using PCL and gelatin lattices as templates, respectively. The scaffolds exhibited uniform pore size and well-interconnected pore structure in three-dimensional (3D) fashion. |