| 초록 |
Bioelectrodes have been widely used for biosensors and other bio-electronic applications. However, the electrical properties of bioelectrodes are commonly impaired in the biological environment due to biofouling. Hence, the development of facile and effective surface modification is needed. Electrochemical method is suitable for bio-electrode coating because it enables selective coating with good reaction control. In this study, we demonstrated electrochemical electrode modification with dopamine-conjugated hyaluronic acid (DA-HA). The modified electrodes exhibit highly hydrophilic surfaces and greatly increased hardness. Besides, the electrochemical impedance of the DA-HA-modified electrodes is similar to bare electrodes. Furthermore, DA-HA-modified electrodes could minimize adhesion of fibroblasts and scar tissue formation. Our novel electrochemical passivation of electrodes using DA-HA can be beneficial for various bioelectrode applications and metallic biomaterial modification. |
