화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2022년 봄 (04/06 ~ 04/08, 대전컨벤션센터)
권호 47권 1호
발표분야 의료용 고분자 부문위원회
제목 Biodegradable poly(glycerol sebacate)-based adhesive with hemispherical concave cups on hexagonal architectures
초록 Among biodegradable materials, poly (glycerol sebacate) (PGS) can be applied to microarchitecture-based tissue adhesive, because it has biodegradable and bioresorbable characteristics, that can induce interfacial adhesion by controlling mechanical properties. Herein, we presented a tissue adhesive fabricated using PGS, which can maintain adhesion even on a wet surface by mimicking the toe pad of a frog. To implement bioinspired adhesive architectures, the particular criteria under which PGS can be patterned were presented using simple models based on the degree of esterification and interfacial energy difference. Based on our investigation, wet adhesion in the adhesive was achieved by replicating the hexagonal micro-channel and concave cup structures existing hierarchically on the toe pad of frogs. The adhesion of PGS ahesive was measured on various organ surfaces, resulting in a stable wet adhesion with clean attachment and biodegradability.
저자 이연수, 김다완, 김진형, 황귀원, 전승환, 방창현
소속 성균관대
키워드 Wet adhesion; biomimetic; biodegradable polymer; tissue adhesive
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