| 초록 |
How to design 3D matrices and nanocarriers with therapeutic actions relevant for the repair and regenerative process of cells and tissues is a key paradigm in ‘next generation biomaterials’. Intrinsic parameters including nanotopological surface, mechanical elasticity, and smart chemistry are simple yet facile tool to trigger initial anchorage of (stem, progenitor) cells and their differentiation toward a preferred lineage. Extrinsic approach to delivering signaling molecules (drugs, growth factors, and genes) in a controlled manner can potentiate the therapeutic functions, like stem cell recruitment, pro-angiogenesis, anti-inflammation, and tissue maturation. Our group has focused on the development of 3D nano-matrices and nanocarriers with unique therapeutic potentials for the repair and regeneration of tissues in nerve, muscle, bone, tooth and the interfacial areas. Today’s talk communicates this field of interest exploited over the last years. |
