| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터) |
| 권호 |
35권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Surface immobilization of PMMA-b-PEG on polydimethylsiloxane and evaluation of cytotoxicity in vitro |
| 초록 |
It demonstrates a simple coating method to immobilize PMMA-b-PEG on polydimethylsiloxane(PDMS) which is a promising packaging material for an implantable biosensors. PDMS has good mechanical properties and, thermal and chemical stability that a coating material requires. However, it is very hydrophobic even in aqueous environments and needs to improve its wettability for a variety of applications in spite of such advantages. We chose PMMA-b-PEG, a terpolymer based on hydrophobic and hydrophilic structures, which attaches diverse surfaces due to its amphiphilicity. The PDMS surface was coated with PMMA-b-PEG solutions at various concentrations. Contact angle was measured to observe stability of PMMA-b-PEG on PDMS, FE-SEM and AFM analysis were performed to observe surface morphology. MTT test was also performed to confirm the possible cytotoxicity of PMMA-b-PEG in vitro. |
| 저자 |
최재유, 정재연, 박성재, 박수범, 이종환, 정걸, 조성인, 현진호
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| 소속 |
서울대 |
| 키워드 |
polydimethylsiloxane; PMMA-b-PEG; cytotoxicity
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| E-Mail |
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