| 학회 | 한국공업화학회 |
| 학술대회 | 2006년 가을 (11/10 ~ 11/11, 경희대학교(수원캠퍼스)) |
| 권호 | 10권 2호 |
| 발표분야 | 나노기술 |
| 제목 | Preparation and release behaviors of temperature-sensitive injectable nanoparticles |
| 초록 | The amphiphilic copolymers composed of chitosan and poly(N-isopropylacrylamide) (PNIPAAm) forms the nanoparticles depending on temperature change. In aqueous condition, chitosan and PNIPAAm chain are both hydrophilic, whereas above the lower critical solution temperature (LCST), PNIPAAm chain becomes hydrophobic. Result that the amphiphilic copolymers forms self-assembled nanoparticles. The properties of PNIPAAm play an important role in controlling the loading and release process. Therefore, it is possible to develop novel injectable drug carriers. |
| 저자 | 정유연, 이상봉, 조계민, 심진기 |
| 소속 | 한국생산기술(연) |
| 키워드 | chitosan; PNIPAAm; amphiphilic; temperature sensitive |
