| 초록 |
In this study, temperature and pH sensitive drug delivery system was prepared. As a temperature sensitive material, PEO fibers were fabricated by using electrospinning method with model drug. Prepared electrospun fibers were inserted in the pH sensitive hydrogel under E-beam irradiation. Finally, temperature and pH sensitive drug delivery system was obtained. The surface morphology was investigated by using FE-SEM. The strength of composite hydrogel was enhanced by addition of electrospun fibers. Drug release experiment was carried out by using UV apparatus. It was confirmed that temperature and pH sensitive drug delivery system was obtained successfully by our preparation method. |
