| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
대학원생 구두발표 (영어발표, 발표15분) |
| 제목 |
Development of hybrid type DES using 3D printing technique for biliary application |
| 초록 |
Self-expandable metal stents (SEMSs) for biliary application can become obstructed over time because of tumor / tissue overgrowth, ingrowth, and biliary sludge. Moreover, metal stents merely promote biliary drainage and have no anti-tumor effect. In contrast, a drug-eluting metallic stent (DES) may provide continuous relief of malignant obstructive jaundice and tumor control. Paclitaxel (PTX), an anti-tumor drug that is demonstrating encouraging activity in human malignancies, is likely to play a major role in cancer chemotherapy. Poly caprolactone (PCL) is one of the most potential candidates for this purpose due to its biodegradability, non-toxicity and biocompatibility to many drugs. In this study, the optimal performance was verified according to the various different kinds of PTX / PCL weight ratio. This study have demonstrated through the new development of hybrid type (blend of PTX / PCL ratio) of drug eluting stent using 3D-printing technique for biliary application. |
| 저자 |
장봉석1, 이민권2, 임동수1, 지소미1, 박원호1
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| 소속 |
1(주)엠아이텍, 2충남대 |
| 키워드 |
hybrid; DES; 3D-printing technique; biliary application
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| E-Mail |
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