| 초록 |
The adhesion property of scaffolds is an key to how long the scaffold remains attached to the tissue and how many cells it can hold. Adhesive scaffolds are cell/gene transferable self-stickers that can enhance wound healing or tissue regeneration. The PVP used in this study reacts with water to cause gelation when used alone, thus it requires a support material that can maintain its shape. The support is an important factor in that the cell acts as a pillar that can grow. As a supporter, PGS, which has elastic properties, was used to obtain a product in the form of a mat that stretches like a parafilm. The experiment was conducted in PGS pre-polymer state for use in electrospinning. It was designed by coaxial electrospinning with pre-PGS and PVP produced 2D fibers and then crosslinked to get the product. The scaffold production conditions were optimized and the applicability for tissue regeneration was examined by analyzing the physical properties of the scaffold. |
