| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 봄 (04/11 ~ 04/12, 대전컨벤션센터) |
| 권호 |
38권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Functional polymer covered magnetic nano particles for MR imaging and photothermal transducer of cancer cells |
| 초록 |
As the field of theranosis has emerged from the converging of therapy with medical imaging, nanoparticle mediated theranosis are increasingly highlighted due to their high therapeutic effectiveness and diagnostic sensitivity. Especially, imaging guided photothermal ablation therapy has gain popularity recently because a specific amount of photoenergy is delivered directly into the tumor mass without side effects. Herein, we introduced a new class of organic-inorganic hybrid nanoparticles for imaging guided localized therapy. In detail, inorganic super-paramagnetic nanoparticles were embedded inside organic polyaniline matrix which enabled both MR iamging and NIR illuminated therapy under intracelluar acidic/oxidative conditions. Fabricated nanoparticles are successfully investigated and We believe that this nanoparticle can be further developed as a cancer diagnostic as well as NIR activable therapy of metastatic cancer cells. |
| 저자 |
이택수, 방도연, 최지혜, 강병훈, 서진석, 허용민, 함승주
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| 소속 |
연세대 |
| 키워드 |
MRI; photothermal therapy; theranosis
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| E-Mail |
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