화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2010년 가을 (10/21 ~ 10/22, 대전컨벤션센터)
권호 16권 2호, p.1544
발표분야 생물화공
제목 Preparation of QDs Entrapped Polymer Nanofibers as a Scaffold for Enzyme Immobilization
초록 In this study, we report the structure and shape of PS-PSMA nanofibers with entrapped QDs, which can be prepared by electrospinning the homogenous mixture of polymers and QDs. Uniformly distributed QDs within the polymer matrix of nanofibers induced high degree of compactness and shape rigidity in the nanofibers and allowed efficient enzyme immobilization. The esterase-nanofiber composites were prepared by fabricating crosslinked enzyme aggregates on the surfaces of nanofibers. Esterase coatings on QDs PS-PSMA nanofibers retained good stability by showing no enzyme activity loss under recycled uses for more than ten times. The present study demonstrates a successful application of QDs PS-PSMA nanofibers for enzyme immobilization for the first time; it is anticipated that this technology would be employed in various enzyme applications due to the easy shape control of the nanofibers.
저자 황이택1, Rameshwar Tatavarty2, 이 현1, 김중배2, 구만복1
소속 1College of Life Sciences and Biotechnology, 2Korea Univ.
키워드 Enzyme Immobilization; Electrospinning; Nanofibers; Quantum dots; Enzyme coatings
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