| 학회 | 한국공업화학회 |
| 학술대회 | 2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 | 22권 2호 |
| 발표분야 | 생물공학_포스터 |
| 제목 | Microwave-Assisted Drying Kinetics and Thermodynamic Analysis of Paclitaxel for Removal of Residual Solvent |
| 초록 | Abstract In this study, we investigated the kinetics and thermodynamics of microwave-assisted drying of paclitaxel for the removal of residual solvent, acetonitrile. The efficiency of microwave-assisted drying increased with increasing drying temperature. When the experimental data were applied to various kinetic models, the Newton model, Page model, and the Geometric model were acceptable. Among the kinetic models, the Page model was the most appropriate. The activation energy Ea of microwave-assisted drying was found to be 46.21 kJ/mol. The Gibbs free energy change was determined to be negative, while enthalpy change and entropy change were positive. These results indicate that this extraction process was spontaneous, endothermic, and irreversible in nature. |
| 저자 | 장원석, 김진현 |
| 소속 | 공주대 |
| 키워드 | Paclitaxel; Microwave-Assisted Drying; Kinetics; Thermodynamics; Residual Solvent |
