| 초록 |
The environmental issues of petroleum-derived plastics have helped to stimulate the interest in natural biodegradable polymers from renewable resources. Among the natural polymers, polyhydroxyalkanoates (PHAs) are biodegradable and biocompatible polyesters produced by a range of microorganisms naturally. So far, more than 150 different monomeric units have been identified, making it possible to produce PHAs with diverse physical and mechanical properties. Unlike PHB homopolymer, PHA copolymers consisting of 3-hydroxybutyrate (C4) and medium-chain-length (C6-C14)-3-hydroxyalkanoates have been expected to be suitable for diverse applications, because they show flexible properties that are comparable to those of commercial petroleum-based plastics. Herein, we explore routes to efficiently synthesize the various types of PHA copolymers from renewable carbon sources by developing the recombinant microbial platform strains. |
