| 초록 |
Hydrogel-based adhesives for bioapplications including transdermal drug delivery, surgical sealants and wound dressing are being actively studied because of their facile fabrication, easy control of mechanical properties, biodegradability, and biocompatibility. Despite the development of many adhesive hydrogels, the adhesive hydrogel has a limit attributed to intrinsic low mechanical properties derived from a large amount of water in the hydrogel. To overcome the limit of conventional adhesive hydrogels, the adhesive hydrogel basically requires high adhesiveness to the surface of the substrate and high toughness which was endurable to large deformation. Here, we propose a super-adhesive triple-network (TN) hydrogel consisting of alginate/polyacrylamide double-network hydrogel and adhesive imidazole-functionalized polymer. The resulting TN hydrogel exhibited significantly high adhesiveness on the substrate, which does not require any surface treatment. In addition, the TN hydrogel has high stability in wet condition without large swelling. This TN hydrogel may offer very facile synthetic method without any additional complicated process for various bioapplications. |
