| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 봄 (04/07 ~ 04/08, 대전컨벤션센터) |
| 권호 |
36권 1호 |
| 발표분야 |
고분자 합성 |
| 제목 |
Synthesis of poly(N-vinyl pyrrolidone)-b-poly(ε-caprolactone) amphiphilic diblock copolymers by combination of ROP and RAFT polymerization |
| 초록 |
Amphiphilic block copolymers composed of biocompatible hydrophilic and hydrophobic blocks have been attracted much attention as nano-sized carriers for poorly water-soluble drugs. In this study, biocompatible poly(N-vinyl pyrrolidone)-b-poly(e-caprolactone) (PVP-b-PCL) diblock copolymer was synthesized by combination of ROP and RAFT. PCL synthesized by ROP was first modified into macro-chain transfer agent (PCL-RAFT), and then RAFT polymerization of N-vinyl pyrrolidone was conducted using PCL-RAFT. It was found that this method could successfully produce PVP-b-PCL diblock copolymer with very narrow molecular weight distribution. |
| 저자 |
유영창, 기보람, 이동욱, 강현욱, 육지호
|
| 소속 |
인하대 |
| 키워드 |
RAFT; ROP; PVP-b-PCL; amphiphilic diblock polymer
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| E-Mail |
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