| 학회 |
한국공업화학회 |
| 학술대회 |
2007년 봄 (05/11 ~ 05/12, 계명대학교) |
| 권호 |
11권 1호 |
| 발표분야 |
콜로이드계면화학 |
| 제목 |
Detection of Chemical and Biological Analytes Using Nanostructured Polydiacetylene Supramolecules |
| 초록 |
Using the mission fluorescence change of conjugated polydiacetylene supramolecules, we demonstrated a specific chemical inclusion complex could be detected (JACS 2005, 127, 17580). In this talk, we present that such fluorescent sensor systems using convenient microarryer can be applied to biological detection (antibody-E. coli cell interaction, protein-protein interaction, and DNA hybridization) as well as chemical detection (α-cyclodextrin and formaldehyde). Such detections are high selective and sensitive. Especially, the detection limit for DNA hybridization (15 base pairs) was determined to be as low as 10 fM, even without any labeling procedure. |
| 저자 |
이길선1, 안동준1, 최현1, 양두호1, 김은진1, 김종만2
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| 소속 |
1고려대, 2한양대 |
| 키워드 |
polydiacetylene; E.coli detection; DNA hybridization; label-free
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| E-Mail |
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