| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 가을 (10/06 ~ 10/08, 대구컨벤션센터(EXCO)) |
| 권호 |
40권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Multilayered scaffolds by sequential electrospinning of microfibrous PLGA and micro-, nano fibrous PLGA/Col/nHA |
| 초록 |
Electrospinning is the widely known technique for the fabrication of nanofibrous scaffolds. PLGA is polyester having biocompatible properties. Collagen is a protein most abundant in the body. Furthermore hydroxyapatite(nHA) has similar structure and composition to natural bone. In this study, dual electrospinning system was employed to fabricate the hybrid microfibrous scaffolds of PLGA and nanofibrous Col/nHA-g. We characterized the electrospun scaffold with various spectroscopic techniques such as TEM, SEM, FTIR and XPS. The results suggested that the PLGA/Col/nHA-g composite scaffolds were successfully fabricated. Proliferation and differenciation have been evaluated using MTT, Alizarin red and Von Kossa assay. PLGA/Col/nHA-g scaffold was found to be more bioactive in comparison to the pristine PLGA scaffolds and PLGA/Col scaffolds. |
| 저자 |
강인규, 권기완, 곽상화
|
| 소속 |
경북대 |
| 키워드 |
PLGA; collagen; HA; elcrtospinning
|
| E-Mail |
|
