| 초록 |
Application of fluorescent conjugated polymers for “amplified” sensing of chemical and biol-ogical analytes has received considerable attention. Recently, synthesis and application of water-soluble poly(para-phenylene) via Suzuki-cross coupling reaction has studied for many resear-chers. We have attempted to synthesize water-soluble poly(para-phenylene) derivatives, such as poly[2,5-bis(4-sulfonatobutoxy)-1,4-phenylene-alt-1,4-phenylene] sodium salt and poly[2,5-bis(6-N,N,N-triethylammonium-1-oxapropyl)-1,4-phenylene-alt-1,4-phenylene] dibromide. We developed a method to introduce a benzaldehyde and 4-(bromopehnyl)-maleimide group, a versatile functional group for bioconjugation, at both ends of PPPs chain. The synthesized polymers showed good solubility in water. The polymer containing benzaldehyde and 4-(bromopehnyl)-maleimide end-group had binding capacity for biological analytes showing fluorescence quenching. |
