화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2014년 가을 (10/06 ~ 10/08, 제주 ICC)
권호 39권 2호
발표분야 의료용 고분자 부문위원회
제목 Preparation of Metal Stents with Silver Particles incorporated in Polymeric membrane and Their Application to Biliary obstruction
초록 Self-expanding bare metal stents (SEBMS) are being commonly used to prevent biliary tract obstruction. For example, ePTFE, polyurethane, and silicone in order to prevent tumor ingrowth through the wire mesh. One of main issues in clinical use of biliary stent is a biofilm formation on the surface of polymeric membranes which lead to stent obstruction. This study was to prepare Ag-incorporated membrane for covering biliary stent and evaluate the application for biliary stent to prevent the formation of biofilm. As a result of antimicrobial test, it was found that antimicrobial effect was significantly decreased on control, but the membrane with Ag-particles continuously maintained its antimicrobial effect even accelerated aging test after 97days at 60 celcius degrees. It was showed that the stent covered with silicone membrane including Ag-particles had a potential to prohibit the formation of biofilm on the surface of membrane from sludge and improve patency in a long term.
저자 장봉석1, 박헌국1, 윤호1, 김선종1, 김은진1, 박도현2
소속 1(주) 엠아이텍, 2서울아산병원 소화기내과
키워드 GI stent; stent; ePTFE; silver particle; biofilm;
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