| 학회 |
한국고분자학회 |
| 학술대회 |
2007년 가을 (10/11 ~ 10/12, 일산킨텍스) |
| 권호 |
32권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Optimization of the cartilaginous tissue formation using human adipose tissue-derived stromal cells and PLCL/Hydrogel scaffolds |
| 초록 |
Human adipose tissue-derived stromal cells (hADSCs) have been studied widely as one of the alternative cell sources in tissue engineering because it is known that they would possess the potentials for multi-lineage differentiations. In our previous studies, it was confirmed that hADSCs would be differentiated to chondrogenic lineage by the micromass culture and the 3-dimensional microenvironments using hydrogel would be beneficial to the formation of cartilaginous tissues. The purpose of this study is to find the optimal conditions of gel concentration and differentiation period for cartilaginous formation using hADSCs and the hybridized scaffold with hydrogels and Poly(lactide-co-caprolacton) (PLCL) scaffolds. This study was performed histological and molecular biological analyses for confirming cartilaginous tissue formation. From the results, the conditions of gel concentration and differentiation period for cartilaginous tissue formation could be optimized. |
| 저자 |
김상희1, 김수현2, 정영미2, 김상헌2, 김영하3, 이종원4, 김수현2
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| 소속 |
1KIST, 2한국과학기술(연), 3광주과학기술원, 4카톨릭대 |
| 키워드 |
cartilaginous tissue formation; human adipose tissue-derived stromal cells
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| E-Mail |
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