| 학회 | 한국화학공학회 |
| 학술대회 | 2003년 봄 (04/25 ~ 04/26, 순천대학교) |
| 권호 | 9권 1호, p.255 |
| 발표분야 | 공정시스템 |
| 제목 | Consistent simplification of stiff metabolic problems |
| 초록 | Metabolic problems for dynamic simulation usually form stiff systems. When a system is stiff, it’s highly possible that model parameters are inaccurate in view of measurability, and numerical algorithms are supposed to require much smaller time step compared to time horizon of the problem, which can result in loss of computational efficiency and accumulation of round-off error. Traditionally, quasi steady state approximation has been used in simplifying stiff dynamic problem. However, scale analyses in QSSA have been dependent on researchers’ experience and intuition about corresponding systems. For practical computer implementation in metabolic problem, it is necessary to establish systematic and consistent approach toward proper model simplification. This paper tried to suggest objective criterion in scale analysis and to derive simple plausible model from complex dynamic one. |
| 저자 | 최준원, 이태용 |
| 소속 | 한국과학기술원 생명화학공학과 |
| 키워드 | metabolic; dynamic; stiff; simplification; reduction |
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