| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 |
20권 1호 |
| 발표분야 |
고분자_포스터 |
| 제목 |
Peptide nanotube effects for fmoc-diphenylalanine peptide hydrogel |
| 초록 |
Hydrogels have enormous potential to be used in biomedical applications due to their high water-holding capacity, suitable mechanical strength, controlled release of the active ingredients, and biocompatibility. However, it is difficult for a single system to satisfy all the above-mentioned requirements. N-fluorenylmethyloxycarbonyl diphenylalanine(Fmoc-FF) forms a hydrogel under physiological conditions. Some Fmoc-FF hydrogel exhibited low stability and will seriously limit their utilization in biomedicine, such as drug delivery. Peptide nanotube(PNT) is selected as a stabilizer. In this study, the Fmoc-FF/PNT hybrid hydrogel was prepared through molecular self-assembly of Fmoc-FF. The main purpose in this research is to improve the stability of Fmoc-FF hydrogels. The hybrid hydrogel containing PNT 7% has enhanced mechanical strength compared with that of Fmoc-FF hydrogel alone. The physicochemical properties of this hybrid hydrogel were investigated. |
| 저자 |
최란주, 기현준, 이경진, 강지선, 홍샘, 윤석일
|
| 소속 |
상명대 |
| 키워드 |
Peptide based hydrogel; peptide nanotube(PNT); physicochemical properties
|
| E-Mail |
|
