| 초록 |
Surface-enhanced Raman spectroscopy (SERS) is emerging technique detecting analytes, though a method to increase signal enhancement for limited and/or small amount analytes is remained unsolved. We developed Ag-chitosan nano-composite layers to increase sensitivity of the paper sensor. In order to amplify a Raman signal, Ag-chitosan nano-composite is manufactured by using layer-by-layer assembly which is a kind of in-situ reducing synthesis. In this presentation, we used rhodamine 6G, methylene blue, and 4-amino-thiophenol as testing analytes. As the layers of nano-composite on paper increasing, signals of analyte increased. It was found that optimum generation of paper sensor inversely dependent on analytes’ size exhibiting less layers are required for larger analytes. In conclusion, it was confirmed by the enhancement of signal that the ‘hot spot’ increased as the number of layers increased. Reliable sensing data was obtained by a simple fabrication using paper. |
