화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 봄 (05/13 ~ 05/14, BEXCO(부산))
권호 14권 1호
발표분야 생물공학: 해양바이오에너지
제목 Sensitive synthetic 5'UTRs for fine-tunable expression in optimum pathway synthesis
초록 “Metabolic Engineering” aims the purposeful redesign of the biological systems and requires the accurate information of the cellular metabolic networks and proper tools for the reconstruction of the biological systems such as the regulatory elements and engineered proteins. Precise control of the expression level is obviously essential for designing the optimized pathways but proper molecular elements to control the expression level is not available at the moment. This presentation will cover the efforts to develop synthetic UTRs to control the expression level precisely and the potentials for the application to the production of biofuels and commodity chemicals including butanol, hydrogen, and amino acid.
저자 정규열, 서상우, 양재성, 김상욱
소속 POSTECH
키워드 pathway synthesis; UTR; tunable expression; synthetic biology
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