화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2022년 봄 (04/06 ~ 04/08, 대전컨벤션센터)
권호 47권 1호
발표분야 기능성 고분자
제목 Molecularly Imprinted Conducting Polymer Film Based on Extended-Gate Field-Effect Transistor for Selective Phenytoin Detection
초록 Phenytoin is known to be one of the most commonly prescribed anticonvulsants for the treatment of epilepsy. A continuous therapeutic monitoring is required to ensure effective treatment without toxicity in therapeutic concentration range from 10 to 20 μg/mL. Up to now, molecular imprinted polymers(MIPs)-based sensing systems have been reported to determine the phenytoin due to their numerous advantages such as simple preparation, high reliability, and stability. In particular, molecularly imprinted conducting polymers(MICP)-based electrochemical sensors have great potential in detecting a target molecule because it can identify the minute changes in potential on the surface of MICP sensor. In this study, we introduce a MICP-based electrochemical sensor with catechol derivatives for detecting phenytoin using an extended-gate field-effect transistor (EG-FET).
저자 양진철, Deepshikha Hazarika, 변제욱, 이규비, 박진영
소속 경북대
키워드 MIP; EG-FET; conducting polymer; phenytoin; sensor; catechol derivatives
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