| 학회 |
한국공업화학회 |
| 학술대회 |
2014년 봄 (04/30 ~ 05/02, 제주국제컨벤션센터) |
| 권호 |
18권 1호 |
| 발표분야 |
생물화학기술의 진보와 전망 |
| 제목 |
Biosilica, Biosilification and Bio-inspried Nanobiomaterials |
| 초록 |
Silica has a wide range of industrial uses and its nontoxic and highly biocompatible characteristics lend well to applications in scaffolds for tissues, drug-delivery system, biosensors and imaging. The discovery of the principle molecules involved in biosilicification both in diatoms (silaffins and polyamines) and sponges (silicateins) brings out understandings about biosilicification and has created a new paradigm for silica synthesis under ambient or mild conditions. The prerequisite for the utilization of biosilicification machinery is the availability of enzymatically active recombinant proteins involved in silica formation. In this study, two alternative silica-forming proteins are focused: CAT, hypothetical cathepsin-like protein from Nematostella vectensis; and SLC, a mutant CAT obtained by mutating residues, including a catalytic cysteine residue, into conserved SIL residues. |
| 저자 |
백승필, 여기백, 장의경, 박기성, Khoa My Nguyen, 기미란
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| 소속 |
고려대 |
| 키워드 |
Biosilica; Biosilification; Diatom; Sponge
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| E-Mail |
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