| 초록 |
Due to the extreme toxicity of chemical warfare agents (CWAs) containing phosphonate linkages, examples include Sarin (GB), Soman (GD), and VX, their detoxification has been extensively explored. Destruction and decontamination of CWAs has received renewed attention given the recent global events such as the conflict and disarmament in Syria and the terror in Malaysia. CWAs containing phosphonate and phosphonothioate are insidious—they effectively inhibit the enzyme acetylcholine esterase, shutting down pulmonary muscle control and causing death by oxygen deprivation within minutes. To date, a variety of catalysts have been discovered to be active for the degradation of nerve agents. Among the most promising for the detoxification of CWAs are a class of porous functional materials named metal-organic frameworks (MOFs). In this study, I summarize recent advances in the development of MOF catalysts and polymer composites for the hydrolysis of nerve agents. |
