| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
고분자합성 |
| 제목 |
Ring-opening Polymerization of α-Amino acid N-Carboxyanhydrides by Employing Carbene Derivatives as a Catalyst |
| 초록 |
A series of polypeptides have been synthesized by ring-opening polymerization of α-amino acid N-carboxyanhydride (NCA) by using 1,3-diisopropylimidazolium hydrogen carbonate as the catalyst. The catalyst was achieved by anion metathesis of imidazolium halides using potassium hydrogen carbonate in methanolic solution, without the need for the prior preparation of free carbene. With this methodology,the ring-opening polymerization of polypeptides are controllable and faster. The control of polymerization was attributed to the strong nucleophilicity of N-heterocyclic carbenes. |
| 저자 |
류런제1, 김일2
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| 소속 |
1BK21 플러스 동남권 화학신기술 창의인재양성사업단, 2부산대 |
| 키워드 |
polypeptide; N-heterocyclic carbene; N-carboxyanhydride; catalysis
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| E-Mail |
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