| 학회 | 한국화학공학회 |
| 학술대회 | 2018년 봄 (04/25 ~ 04/27, 창원컨벤션센터) |
| 권호 | 24권 1호, p.374 |
| 발표분야 | 생물화공 |
| 제목 | Production of gamma-aminobutyrate (GABA) in recombinant Corynebacterium glutamicum strains |
| 초록 | Gamma-aminobutyrate (GABA) is a non-protein amino acid that can be used in food and pharmaceutical industry. Moreover, recently, application of GABA as a building block chemical is extensively investigated in chemical industry such as use as precursor for the synthesis of 2-pyrrolidone and monomer for the synthesis of nylon 4. Recombinant microorganisms have been constructed for the production of GABA, which include recombinant Escherichia coli and Corynebacterium glutamicum. In this presentation, we report development of recombinant C. glutamicum strains expressing glutamate decarboxylase mutant for the high-level production of GABA from renewable resources. Detailed results will be presented. Acknowledgements This work was supported by the Mid-career Researcher Program from the Ministry of Science and ICT (MSIT) through the National Research Foundation (NRF) of Korea (NRF-2016R1A2B4008707), a basic research grant from the KRIBB, and the Ligin Biorefinery from MSIT through the NRF of Korea (NRF-2017M1A2A2087135) |
| 저자 | 박시재1, 주정찬2, 김희택2, 바리투고 케이앤1 |
| 소속 | 1이화여자대, 2한국화학(연) |
| 키워드 | 생물화공 |
| 원문파일 | 초록 보기 |
