| 초록 |
This study proposes a simple, new way of producing porous bioceramics with highly aligned pore structures for providing excellent bone regeneration because of their three-dimensionally interconnected pores by lithography-based additive manufacturing (A.M.) technique which adopted the principle of tape-casting using photo-curable ceramic suspension included freezing vehicles and high solid loading (= 50vol.%). In this method, CaP (calcium phosphate) comprising of hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) was mixed with Camphene/Camphor which are freezing vehicles and UDMA (Urethane dimethacrylate) which is a photo-curable monomer. Porous ceramic structures were produced by suspensions with various initial freezing vehicle contents (40, 50, 60 vol.%) at each specific temperatures ranging from 42 to 47℃, which resulted in the dendritic growh of camphene crystals during A.M. process. After frozen camphene removed completely by freeze drying and its were sintered at 1250℃ for 3h. As a result of observing the microstructure using scanning electron microscope, all of the sintered bodies showed similar 3D interconnected pore morphologies and excellent densification with negligible pores were observed for CaP frameworks of a sintered body. In addition, as a result of mercury porosimetry, porosities and pore size increased according to initial contents of freezing vehicles from 26 to 53 vol.% and its corresponded with microstructure images using SEM. On the other hand, the flexural strength decreased considerably from 32.4 ± 2 to 10.4 ± 0.8 MPa, respectively, due to the increase in the porosity of the samples. |
