| 학회 |
한국공업화학회 |
| 학술대회 |
2012년 가을 (10/31 ~ 11/02, 대전컨벤션센터) |
| 권호 |
16권 2호 |
| 발표분야 |
포스터-정밀화학 |
| 제목 |
RGD Peptide Conjugated Chitosan Nanoparticles to angiogenesis |
| 초록 |
Targeted polymeric gene delivery system, chitosan-PEG-RGD was developed by incorporating the αvβ3 integrin-binding RGD peptide (A dimeric RGD peptide, H-Glu[cyclo(Arg-Gly-Asp-D-Phe-Lys)]2, was recently reported to possess high affinity for αvβ3 integrin, into the cationic polymer, CPRGD via a hydrophilic polyethylene glycol (PEG) spacer. We synthesized chitosan-PEG-RGD conjugate and the physicochemical properties of the chitosan-PEG-RGD were investigated by using 1H-NMR, Dynamic light scattering and Transmission Electron Microscope (TEM). The LMPR Nanoparticle was investigated to gene carrier. |
| 저자 |
홍락준, 남정표, 손동희, 김원석, 최창용, 나재운, 장미경
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| 소속 |
순천대 |
| 키워드 |
chitosan; siRNA; angiogenesis; RGD peptide
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| E-Mail |
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