| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 가을 (11/08 ~ 11/10, 부산 벡스코(BEXCO)) |
| 권호 |
21권 2호 |
| 발표분야 |
생물공학_포스터 |
| 제목 |
Study on the features of subsites in xylanases |
| 초록 |
The crystal structures for the GH10 and GH11 family xylanases revealed that both the families have different structural folds. The family 10 xylanases consists of (α/β)8-barrel type of fold. On the other hand, the family 11 xylanases shows a β-jelly roll type of fold consisting of antiparallel beta-sheets linked by loops and short helices which resembles the shape of a right hand. The substrate binding site that accommodate xylose moiety is known as a subsite. These subsites often contain residues such as tyrosine and tryptophan which can pack effectively against the xylose ring and other polar amino acids which can form hydrogen bonds with the substrate molecule. In this study, the sequence and structural features of the subsites in the xyalanases were chraterized by sequence and structural alignments. The substrate binding modes in the subsites were also computationally characterized. |
| 저자 |
Bharat MADAN, 이선구
|
| 소속 |
부산대 |
| 키워드 |
xylanase; subsite; alignments
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| E-Mail |
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