화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2013년 가을 (10/23 ~ 10/25, 대구 EXCO)
권호 19권 2호, p.1529
발표분야 생물화공
제목 High-level production of 5-aminovalerate from L-lysine  by recombinant Escherichia coli
초록 Production of biomass-driven chemicals has attracted a lot of attentions as global concerns on environmental problems and availability of petroleum resources increase. 5-aminovalerate (5AVA) is a five carbon amino acid that can be used for synthesizing C5 platform chemicals, such as 1,5-propanediol, glutarate, 5-hydroxyvalerate, and valerolactam. Among these chemicals, valerolactam prepared easily by a simple chemical reaction from 5AVA can be used as the monomer of nylon 5. For this reason, 5AVA has been recently receiving attention as one of the promising building-block chemicals for biopolymer synthesis. In this study, we report high-level conversion of L-lysine into 5AVA by employing recombinant E. coli, expressing Psedomonas putida davAB genes, cultured to high density by fed batch cultivation as a whole cell catalyst. Detailed results will be presented in this presentation.
저자 오영훈1, 노 원1, 송봉근1, 제갈종건1, 이승환1, 박시재2
소속 1한국화학(연), 2명지대
키워드 5-aminovalerate; L-lysine; Escherichia coli
E-Mail parksj93@mju.ac.kr
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